Description
Agilent G1311-67701
Technical Specifications
Brand: Agilent Technologies
Model: G1311-67701
Component type: Multi Channel Gradient Valve assembly
Compatible systems: Agilent 1100 series, Agilent 1200 series HPLC
Compatible pump: G1311A Quaternary Pump
Channel count: 4 solvent channels
Valve function: Proportional solvent mixing for gradient elution
Pressure class: Designed for low-pressure solvent proportioning upstream of the pump head
Certifications: CE marking applicable per Agilent HPLC system compliance
Functional Features
Four-channel solvent proportioning for gradient HPLC methods
Precise control of mobile phase composition
Integrated valve assembly for direct replacement in G1311A pumps
Compatible with common HPLC solvents including water, methanol, acetonitrile, and buffer solutions
Designed for reproducible gradient profiles
Supports isocratic and gradient elution modes
Field-replaceable assembly for maintenance and repair
Factory-tested valve performance for consistent flow distribution
Application Scenarios
Pharmaceutical quality control and method development
Environmental water and soil analysis
Food and beverage testing
Chemical and petrochemical analysis
Clinical and biomedical research
Academic and university analytical laboratories
Contract research organization testing
Regulatory compliance testing under GLP conditions
Performance Parameters
Number of solvent channels: 4
Valve type: Proportional mixing valve
Pressure region: Low-pressure solvent selection side
Flow control: Proportional to pump suction demand
Gradient accuracy: Dependent on complete pump system calibration
Leak integrity: Sealed assembly design for solvent compatibility
Service life: Determined by solvent type, buffer use, and maintenance schedule
Material Composition
Chemically resistant valve body materials
PTFE or fluoropolymer wetted flow paths
Stainless steel fluid connections
Elastomeric seals compatible with HPLC solvents
Solenoid or proportional actuator components
Internal flow channels machined for low dead volume
Structural Features
Compact valve assembly designed for internal pump installation
Multiple solvent inlet ports for four-channel connection
Single mixed-solvent outlet to the pump inlet
Electrical connector for pump controller communication
Mounting interface matched to G1311A pump chassis
Sealed fluid path to prevent solvent leakage
Labeled solvent channel positions for correct installation
Working Principle
The gradient valve receives control signals from the quaternary pump controller and opens each solvent channel in a timed sequence. During each pump suction cycle, the valve proportionally connects the four solvent lines to create the required mobile phase composition. The mixed solvent is drawn into the pump head, compressed, and delivered to the HPLC column. By adjusting the opening ratio of each channel, the system generates precise linear or curved gradient profiles for chromatographic separation.
Installation Requirements
Power off the HPLC system before removing the pump cover
Relieve solvent line pressure before disconnecting tubing
Label all solvent inlet lines to avoid channel misassignment
Install the valve assembly in the correct orientation inside the G1311A pump
Reconnect solvent lines to the correct inlet ports
Prime all four channels after installation to remove air
Run a system leak test before starting analytical runs
Update maintenance records after replacement
Usage Precautions
Use only with compatible Agilent 1100/1200 series quaternary pumps
Do not install on binary pump models unless explicitly confirmed
Avoid using highly corrosive or precipitating solvents without proper flushing
Flush buffer-containing mobile phases with water after each run
Replace worn solvent inlet filters to protect the valve
Do not overtighten fluid fittings during installation
Verify gradient accuracy after replacement using a standard test method
Keep the pump interior dry and free of solvent accumulation
Store spare valves in clean, sealed packaging
